Genome-wide differential methylation analyses identifies methylation signatures of male infertility
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چکیده
منابع مشابه
Genome-Wide Methylation Analyses in Glioblastoma Multiforme
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متن کاملDNA methylation and male infertility.
Male infertility is one of the biggest concerns of today's health care community. In the US and other developed countries, approximately 70% of infertility among couples is attributed to male reproductive failure. Alterations in reproductive organ development and sperm production have been listed as the major causes of this phenomenon. Sex determination and differentiation, X chromosome inactiv...
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Cytosine methylation is the most common covalent modification of DNA in eukaryotes. DNA methylation has an important role in many aspects of biology, including development and disease. Methylation can be detected using bisulfite conversion, methylation-sensitive restriction enzymes, methyl-binding proteins and anti-methylcytosine antibodies. Combining these techniques with DNA microarrays and h...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2018
ISSN: 0268-1161,1460-2350
DOI: 10.1093/humrep/dey319